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Vántus, T, Vertommen, D, Saelens, X, Rykx, A, De Kimpe, L, Vancauwenbergh, S, Mikhalap, S, Waelkens, E, Kéri, G, Seufferlein, T, Vandenabeele, P, Rider, M, Vandenheede, J, Van Lint, J.
Doxorubicin-induced activation of protein kinase D1 through caspase-mediated proteolytic cleavage: Identification of two cleavage sites by microsequencing
Cell Signal 16, 703-709, 2004. (Epub ---)

Assefa, Z, Garmyn, M, Vantieghem, A, Declercq, W, Vandenabeele, P, Vandenheede, JR, Agostinis, P.
Ultraviolet B radiation-induced apoptosis in human keratinocytes: Cytosolic activation of procaspase-8 and the role of Bcl-2
FEBS Lett 540, 125-132, 2003. (Epub ---)

Frame, MJ, Tate, R, Adams, DR, Morgan, KM, Houslay, MD, Vandenabeele, P, Pyne, NJ.
Interaction of caspase-3 with the cyclic GMP binding cyclic GMP specific phosphodiesterase (PDE5a1)
Eur J Biochem 270, 962-970, 2003. (Epub ---)

Fratelli, M, Minto, M, Crespi, A, Erba, E, Vandenabeele, P, Del Soldato, P, Ghezzi, P.
Inhibition of nuclear factor-kB by a nitro-derivative of flurbiprofen: A possible mechanism for antiinflammatory and antiproliferative effect
Antioxid Redox Signal 5, 229-235, 2003. (Epub ---)

Hunter, I, Cobban, HJ, Vandenabeele, P, MacEwan, DJ, Nixon, GF.
Tumor necrosis factor-alpha-induced activation of RhoA in airway smooth muscle cells: Role in the Ca2+ sensitization of myosin light chain20 phosphorylation
Mol Pharmacol 63, 714-721, 2003. (Epub ---)

Jupp, OJ, Vandenabeele, P, MacEwan, DJ.
Distinct regulation of cytosolic phospholipase A2 phosphorylation, translocation, proteolysis and activation by tumour necrosis factor-receptor subtypes
Biochem J 374, 453-461, 2003. (Epub ---)

Kahns, S, Kalai, M, Jakobsen, LD, Clark, BFC, Vandenabeele, P, Jensen, PH.
Caspase-1 and caspase-8 cleave and inactivate cellular parkin
J Biol Chem 278, 23376-23380, 2003. (Epub 2003 Apr 11)

Kalai, M, Lamkanfi, M, Denecker, G, Boogmans, M, Lippens, S, Meeus, A, Declercq, W, Vandenabeele, P.
Regulation of the expression and processing of caspase-12
J Cell Biol 162, 457-467, 2003. (Epub 2003 Jul 28)

Krysko, DV, Brouckaert, G, Kalai, M, Vandenabeele, P, D'Herde, K.
Mechanisms of internalization of apoptotic and necrotic L929 cells by a macrophage cell line studied by electron microscopy
J Morphol 258, 336-345, 2003. (Epub 2003 Sep 30)

Lamkanfi, M, Declercq, W, Depuydt, B, Kalai, M, Saelens, X, Vandenabeele, P.
The caspase family
In Caspases-Their Role in Cell Death and Cell Survival. (Los, M & Walczak, H, eds.), Georgetown/New York, Landes Bioscience/Kluwer Academic-Plenum Publishers, pp. 1-40, 2003. (Epub ---)

Lauwaet, T, Oliveira, MJ, Callewaert, B, De Bruyne, G, Saelens, X, Ankri, S, Vandenabeele, P, Mirelman, D, Mareel, M, Leroy, A.
Proteolysis of enteric cell villin by Entamoeba histolytica cysteine proteinases
J Biol Chem 278, 22650-22656, 2003. (Epub 2003 Apr 10)

Lippens, S, VandenBroecke, C, Van Damme, E, Tschachler, E, Vandenabeele, P, Declercq, W.
Caspase-14 is expressed in the epidermis, the choroid plexus, the retinal pigment epithelium and thymic Hassall's bodies
Cell Death Differ 10, 257-259, 2003. (Epub ---)

Littlejohn, AF, Tucker, SJ, Mohamed, AAA, McKay, S, Helms, MJ, Vandenabeele, P, MacEwan, DJ.
Modulation by caspases of tumor necrosis factor-stimulated c-Jun N-terminal kinase activation but not nuclear factor-kB signaling
Biochem Pharmacol 65, 91-99, 2003. (Epub ---)

Malmegrim de Farias, KCR, Saelens, X, Pruijn, GJM, Vandenabeele, P, van Venrooij, WJ.
Caspase-mediated cleavage of the U snRNP-associated Sm-F protein during apoptosis
Cell Death Differ 10, 570-579, 2003. (Epub ---)

Rozman-Pungercar, J, Kopitar-Jerala, N, Bogyo, M, Turk, D, Vasiljeva, O, Stefe, I, Vandenabeele, P, Bromme, D, Puizdar, V, Fonovic, M, Trstenjak-Prebanda, M, Dolenc, I, Turk, V, Turk, B.
Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity
Cell Death Differ 10, 881-888, 2003. (Epub ---)

Saelens, X, Vandenabeele, P.
Type II autophagic cell death and death-associated protein kinases
Chemtracts, Biochem Mol Biol 16, 387-392, 2003. (Epub ---)

Vanden Berghe, T, Kalai, M, van Loo, G, Declercq, W, Vandenabeele, P.
Disruption of HSP90 function reverts tumor necrosis factor-induced necrosis to apoptosis
J Biol Chem 278, 5622–5629, 2003. (Epub 2002 Nov 18)

van Gurp, M, Festjens, N, van Loo, G, Saelens, X, Vandenabeele, P.
Mitochondrial intermembrane proteins in cell death
Biochem Biophys Res Commun 304, 487-497, 2003. (Epub ---)

van Loo, G, Lippens, S, Hahne, M, Matthijssens, F, Declercq, W, Saelens, X, Vandenabeele, P.
A Bcl-2 transgene expressed in hepatocytes does not protect mice from fulminant liver destruction induced by Fas ligand
Cytokine 22, 62-70, 2003. (Epub ---)

Beyaert, R, van Loo, G, Heyninck, K, Vandenabeele, P.
Signaling to gene activation and cell death by tumor necrosis factor receptors and Fas
Int Rev Cytol 214, 225-272, 2002. (Epub ---)

Kalai, M, van Loo, G, Vanden Berghe, T, Meeus, A, Burm, W, Saelens, X, Vandenabeele, P.
Tipping the balance between necrosis and apoptosis in human and murine cells treated with interferon and dsRNA
Cell Death Differ 9, 981-994, 2002. (Epub ---)

Lamkanfi, M, Declercq, W, Kalai, M, Saelens, X, Vandenabeele, P.
Alice in caspase land. A phylogenetic analysis of caspases from worm to man
Cell Death Differ 9, 358-361, 2002. (Epub ---)

McFarlane, SM, Pashmi, G, Connell, MC, Littlejohn, AF, Tucker, SJ, Vandenabeele, P, MacEwan, DJ.
Differential activation of nuclear factor-kB by tumour necrosis factor receptor subtypes. TNFR1 predominates whereas TNFR2 activates transcription poorly
FEBS Lett 515, 119-126, 2002. (Epub ---)

Mohamed, AAA, Jupp, OJ, Anderson, HM, Littlejohn, AF, Vandenabeele, P, MacEwan, DJ.
Tumour necrosis factor-induced activation of c-Jun N-terminal kinase is sensitive to caspase-dependent modulation while activation of mitogen-activated protein kinase (MAPK) or p38 MAPK is not
Biochem J 366, 145-155, 2002. (Epub ---)

Pollock, J, McFarlane, SM, Connell, MC, Zehavi, U, Vandenabeele, P, MacEwan, DJ, Scott, RH.
TNF-a receptors simultaneously activate Ca2+ mobilisation and stress kinases in cultured sensory neurones
Neuropharmacology 42, 93-106, 2002. (Epub ---)

Rendl, M, Ban, J, Mrass, P, Mayer, C, Lengauer, B, Eckhart, L, Declercq, W, Tschachler, E.
Caspase-14 expression by epidermal keratinocytes is regulated by retinoids in a differentiation-associated manner
J Invest Dermatol 119, 1150-1155, 2002. (Epub ---)

Storey, H, Stewart, A, Vandenabeele, P, Luzio, JP.
The p55 tumour necrosis factor receptor TNFR1 contains a trans-Golgi network localization signal in the C-terminal region of its cytoplasmic tail
Biochem J 366, 15-22, 2002. (Epub ---)

van Loo, G, Demol, H, van Gurp, M, Hoorelbeke, B, Schotte, P, Beyaert, R, Zhivotovsky, B, Gevaert, K, Declercq, W, Vandekerckhove, J, Vandenabeele, P.
A matrix-assisted laser desorption ionization post-source decay (MALDI-PSD) analysis of proteins released from isolated liver mitochondria treated with recombinant truncated Bid
Cell Death Differ 9, 301-308, 2002. (Epub ---)

van Loo, G, Saelens, X, Matthijssens, F, Schotte, P, Beyaert, R, Declercq, W, Vandenabeele, P.
Caspases are not localized in mitochondria during life or death
Cell Death Differ 9, 1207-1211, 2002. (Epub ---)

van Loo, G, Saelens, X, van Gurp, M, MacFarlane, M, Martin, SJ, Vandenabeele, P.
The role of mitochondrial factors in apoptosis: A Russian roulette with more than one bullet
Cell Death Differ 9, 1031-1042, 2002. (Epub ---)

van Loo, G, van Gurp, M, Depuydt, B, Srinivasula, SM, Rodriguez, I, Alnemri, ES, Gevaert, K, Vandekerckhove, J, Declercq, W, Vandenabeele, P.
The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity
Cell Death Differ 9, 20-26, 2002. (Epub ---)

Varghese, J, Sade, H, Vandenabeele, P, Sarin, A.
Head involution defective (Hid)-triggered apoptosis requires caspase-8 but not FADD (Fas-associated death domain) and is regulated by Erk in mammalian cells
J Biol Chem 277, 35097–35104, 2002. (Epub 2002 Jul 16)

Ameloot, P, Declercq, W, Fiers, W, Vandenabeele, P, Brouckaert, P.
Heterotrimers formed by tumor necrosis factors of different species or muteins
J Biol Chem 276, 27098-27103, 2001. (Epub 2001 May 22)

Ameloot, P, Fiers, W, De Bleser, P, Ware, CF, Vandenabeele, P, Brouckaert, P.
Identification of tumor necrosis factor (TNF) amino acids crucial for binding to the murine p75 TNF receptor and construction of receptor-selective mutants
J Biol Chem 276, 37426-37430, 2001. (Epub 2001 Jul 11)

Daemen, MARC, Denecker, G, van 't Veer, C, Wolfs, TGAM, Vandenabeele, P, Buurman, WA.
Activated caspase-1 is not a central mediator of inflammation in the course of ischemia-reperfusion
Transplantation 71, 778-784, 2001. (Epub ---)

Denecker, G, Declercq, W, Geuijen, CAW, Boland, A, Benabdillah, R, van Gurp, M, Sory, M-P, Vandenabeele, P, Cornelis, GR.
Yersinia enterocolitica YopP-induced apoptosis of macrophages involves the apoptotic signaling cascade upstream of Bid
J Biol Chem 276, 19706-19714, 2001. (Epub 2001 Mar 14)

Denecker, G, Vercammen, D, Declercq, W, Vandenabeele, P.
Apoptotic and necrotic cell death induced by death domain receptors
Cell Mol Life Sci 58, 356-370, 2001. (Epub ---)

Denecker, G, Vercammen, D, Steemans, M, Vanden Berghe, T, Brouckaert, G, van Loo, G, Zhivotovsky, B, Fiers, W, Grooten, J, Declercq, W, Vandenabeele, P.
Death receptor-induced apoptotic and necrotic cell death: Differential role of caspases and mitochondria
Cell Death Differ 8, 829-840, 2001. (Epub ---)

Frame, M, Wan, KF, Tate, R, Vandenabeele, P, Pyne, NJ.
The g subunit of the rod photoreceptor cGMP phosphodiesterase can modulate the proteolysis of two cGMP binding cGMP-specific phosphodiesterases (PDE6 and PDE5) by caspase-3
Cell Signal 13, 735-741, 2001. (Epub ---)

Jupp, OJ, McFarlane, SM, Anderson, HM, Littlejohn, AF, Mohamed, AAA, MacKay, RH, Vandenabeele, P, MacEwan, DJ.
Type II tumour necrosis factor-alpha receptor (TNFR2) activates c-Jun N-terminal kinase (JNK) but not mitogen-activated protein kinase (MAPK) or p38 MAPK pathways
Biochem J 359, 525-535, 2001. (Epub ---)

Marti, A, Ritter, PM, Jäger, R, Lazar, H, Baltzer, A, Schenkel, J, Declercq, W, Vandenabeele, P, Jaggi, R.
Mouse mammary gland involution is associated with cytochrome c release and caspase activation
Mech Dev 104, 89-98, 2001. (Epub ---)

McFarlane, SM, Jupp, OJ, Cobban, HJ, Hunter, I, Anderson, HM, Vandenabeele, P, Nixon, GF, MacEwan, DJ.
Stimulation of stress-activated but not mitogen-activated protein kinases by tumour necrosis factor receptor subtypes in airway smooth muscle
Biochem Pharmacol 61, 749-759, 2001. (Epub ---)

Saelens, X, Kalai, M, Vandenabeele, P.
Translation inhibition in apoptosis. Caspase-dependent PKR activation and eIF2-a phosphorylation
J Biol Chem 276, 41620-41628, 2001. (Epub 2001 Sep 12)

Schotte, P, van Loo, G, Carpentier, I, Vandenabeele, P, Beyaert, R.
Lithium sensitizes tumor cells in an NF-kB-independent way to caspase activation and apoptosis induced by tumor necrosis factor (TNF). Evidence for a role of the TNF receptor-associated death domain protein
J Biol Chem 276, 25939-25945, 2001. (Epub 2001 May 7)

Shalak, V, Kaminska, M, Mitnacht-Kraus, R, Vandenabeele, P, Clauss, M, Mirande, M.
The EMAPII cytokine is released from the mammalian multisynthetase complex after cleavage of its p43/proEMAPII component
J Biol Chem 276, 23769-23776, 2001. (Epub 2001 Apr 16)

Vanderheyde, N, Aksoy, E, Amraoui, Z, Vandenabeele, P, Goldman, M, Willems, F.
Tumoricidal activity of monocyte-derived dendritic cells: Evidence for a caspase-8-dependent, Fas-associated death domain-independent mechanism
J Immunol 167, 3565-3569, 2001. (Epub ---)

van Loo, G, Schotte, P, van Gurp, M, Demol, H, Hoorelbeke, B, Gevaert, K, Rodriguez, I, Ruiz-Carrillo, A, Vandekerckhove, J, Declercq, W, Beyaert, R, Vandenabeele, P.
Endonuclease G: A mitochondrial protein released in apoptosis and involved in caspase-independent DNA degradation
Cell Death Differ 8, 1136-1142, 2001. (Epub ---)

Vantieghem, A, Xu, Y, Declercq, W, Vandenabeele, P, Denecker, G, Vandenheede, JR, Merlevede, W, de Witte, PA, Agostinis, P.
Different pathways mediate cytochrome c release after photodynamic therapy with hypericin
Photochem Photobiol 74, 133-142, 2001. (Epub ---)

Vántus, T, Kéri, G, Krivickiene, Z, Valius, M, Steták, A, Keppens, S, Csermely, P, Bauer, PI, Bökönyi, G, Declercq, W, Vandenabeele, P, Merlevede, W, Vandenheede, JR.
The somatostatin analogue TT-232 induces apoptosis in A431 cells. Sustained activation of stress-activated kinases and inhibition of signalling to extracellular signal-regulated kinases
Cell Signal 13, 717-725, 2001. (Epub ---)

Assefa, Z, Vantieghem, A, Garmyn, M, Declercq, W, Vandenabeele, P, Vandenheede, JR, Bouillon, R, Merlevede, W, Agostinis, P.
p38 Mitogen-activated protein kinase regulates a novel, caspase-independent pathway for the mitochondrial cytochrome c release in ultraviolet B radiation-induced apoptosis
J Biol Chem 275, 21416-21421, 2000. (Epub ---)

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