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Broos, K, Lecocq, Q, Xavier, C, Bridoux, J, Nguyen, TT, Corthals, J, Schoonooghe, S, Lion, E, Raes, G, Keyaerts, M, Devoogdt, N, Breckpot, K.
Evaluating a Single Domain Antibody Targeting Human PD-L1 as a Nuclear Imaging and Therapeutic Agent
Cancers (Basel) 11, 6, 2019. (Epub 2019 Jun 21)

Bruger, AM, Dorhoi, A, Esendagli, G, Barczyk-Kahlert, K, van der Bruggen, P, Lipoldova, M, Perecko, T, Santibanez, J, Saraiva, M, Van Ginderachter, JA, Brandau, S.
How to measure the immunosuppressive activity of MDSC: assays, problems and potential solutions
Cancer Immunol Immunother 68, 631-644, 2019. (Epub 2018 May 21)

De Veirman, K, Menu, E, Maes, K, De Beule, N, De Smedt, E, Maes, A, Vlummens, P, Fostier, K, Kassambara, A, Moreaux, J, Van Ginderachter, JA, De Bruyne, E, Vanderkerken, K, Van Valckenborgh, E.
Myeloid-derived suppressor cells induce multiple myeloma cell survival by activating the AMPK pathway
Cancer Lett 442, 233-241, 2019. (Epub 2018 Nov 9)

De Vlaeminck, Y, Lecocq, Q, Giron, P, Heirman, C, Geeraerts, X, Bolli, E, Movahedi, K, Massa, S, Schoonooghe, S, Thielemans, K, Goyvaerts, C, Van Ginderachter, JA, Breckpot, K.
Single-domain antibody fusion proteins can target and shuttle functional proteins into macrophage mannose receptor expressing macrophages
J Control Release 299, 107-120, 2019. (Epub 2019 Feb 21)

Hanoteau, A, Newton, JM, Krupar, R, Huang, C, Liu, HC, Gaspero, A, Gartrell, RD, Saenger, YM, Hart, TD, Santegoets, SJ, Laoui, D, Spanos, C, Parikh, F, Jayaraman, P, Zhang, B, Van der Burg, SH, Van Ginderachter, JA, Melief, CJM, Sikora, AG.
Tumor microenvironment modulation enhances immunologic benefit of chemoradiotherapy
J Immunother Cancer 7, 10, 2019. (Epub 2019 Jan 15)

Laoui, D, Van Overmeire, E, Abels, C, Keirsse, J, Van Ginderachter, JA.
Adoptive Transfer of Monocytes Sorted from Bone Marrow
Bio-Protocol 9, , 2019. (Epub 2019 Jan 5)

Murgaski, A, Bardet, PMR, Arnouk, SM, Clappaert, EJ, Laoui, D.
Unleashing Tumour-Dendritic Cells to Fight Cancer by Tackling Their Three A's: Abundance, Activation and Antigen-Delivery
Cancers (Basel) , 11, 2019. (Epub 2019 May 14)

Umansky, V, Adema, GJ, Baran, J, Brandau, S, Van Ginderachter, JA, Hu, X, Jablonska, J, Mojsilovic, S, Papadaki, HA, Pico de Coana, Y, Santegoets, KCM, Santibanez, JF, Serre, K, Si, Y, Sieminska, I, Velegraki, M, Fridlender, ZG.
Interactions among myeloid regulatory cells in cancer
Cancer Immunol Immunother 68, 645-660, 2019. (Epub 2018 Jul 12)

Van Hove, H, Martens, L, Scheyltjens, I, De Vlaminck, K, Pombo Antunes, AR, De Prijck, S, Vandamme, N, De Schepper, S, Van Isterdael, G, Scott, CL, Aerts, J, Berx, G, Boeckxstaens, GE, Vandenbroucke, RE, Vereecke, L, Moechars, D, Guilliams, M, Van Ginderachter, JA, Saeys, Y, Movahedi, K.
A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment
Nat Neurosci 22, 10211035, 2019. (Epub 2019 May 6)

Vriens, K, Christen, S, Parik, S, Broekaert, D, Yoshinaga, K, Talebi, A, Dehairs, J, Escalona-Noguero, C, Schmieder, R, Cornfield, T, Charlton, C, Romero-Perez, L, Rossi, M, Rinaldi, G, Orth, MF, Boon, R, Kerstens, A, Kwan, SY, Faubert, B, et al..
Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity
Nature 566, 403406, 2019. (Epub 2019 Feb 6)

Willebrand, R, Hamad, I, Van Zeebroeck, L, Kiss, M, Bruderek, K, Geuzens, A, Swinnen, D, Corte-Real, BF, Marko, L, Lebegge, E, Laoui, D, Kemna, J, Kammertoens, T, Brandau, S, Van Ginderachter, JA, Kleinewietfeld, M.
High Salt Inhibits Tumor Growth by Enhancing Anti-tumor Immunity
Front Immunol 10, 1141, 2019. (Epub 2019 Jun 4)

Xavier, C, Blykers, A, Laoui, D, Bolli, E, Vaneyken, I, Bridoux, J, Baudhuin, H, Raes, G, Everaert, H, Movahedi, K, Van Ginderachter, JA, Devoogdt, N, Caveliers, V, Lahoutte, T, Keyaerts, M.
Clinical Translation of [(68)Ga]Ga-NOTA-anti-MMR-sdAb for PET/CT Imaging of Protumorigenic Macrophages
Mol Imaging Biol , in press, 2019. (Epub 2019 Jan 22)

Bala, G, Baudhuin, H, Remory, I, Gillis, K, Debie, P, Krasniqi, A, Lahoutte, T, Raes, G, Devoogdt, N, Cosyns, B, Hernot, S.
Evaluation of [(99m)Tc]Radiolabeled Macrophage Mannose Receptor-Specific Nanobodies for Targeting of Atherosclerotic Lesions in Mice
Mol Imaging Biol 20, 260-267, 2018. (Epub 2017 Sep 5)

Bonelli, S, Geeraerts, X, Bolli, E, Keirsse, J, Kiss, M, Pombo Antunes, AR, Van Damme, H, De Vlaminck, K, Movahedi, K, Laoui, D, Raes, G, Van Ginderachter, JA.
Beyond the M-CSF receptor: novel therapeutic targets in tumor-associated macrophages
FEBS J 285, 777-787, 2018. (Epub 2017 Aug 20)

Broos, K, Lecocq, Q, Raes, G, Devoogdt, N, Keyaerts, M, Breckpot, K.
Noninvasive imaging of the PD-1:PD-L1 immune checkpoint: Embracing nuclear medicine for the benefit of personalized immunotherapy
Theranostics 8, 3559-3570, 2018. (Epub 2018 Jun 7)

Caljon, G, Mabille, D, Stijlemans, B, De Trez, C, Mazzone, M, Tacchini-Cottier, F, Malissen, M, Van Ginderachter, J.A., Magez, S, De Baetselier, P, Van Den Abbeele, J.
Neutrophils enhance early Trypanosoma brucei infection onset
Sci Rep 8, 11203, 2018. (Epub 2018 Jul 25)

Clappaert, EJ, Murgaski, A, Van Damme, H, Kiss, M, Laoui, D.
Diamonds in the Rough: Harnessing Tumor-Associated Myeloid Cells for Cancer Therapy
Front Immunol 9, 2250, 2018. (Epub 2018 Oct 24)

Kauffmann, F, Meert, E, de Jonge, K, Elkrim, Y, Hanot Mambres, D, Denis, O, Muraille, E, Magez, S, De Trez, C.
STAT6 Mediates Footpad Immunopathology in the Absence of IL-12p40 Following Infection of Susceptible BALB/c Mice With Leishmania major
Front Immunol 9, 503, 2018. (Epub 2018 Mar 14)

Keirsse, J, Van Damme, H, Geeraerts, X, Beschin, A, Raes, G, Van Ginderachter, JA.
The role of hepatic macrophages in liver metastasis
Cell Immunol 330, 202-215, 2018. (Epub 2018 Apr 6)

Kiss, M, Van Gassen, S, Movahedi, K, Saeys, Y, Laoui, D.
Myeloid cell heterogeneity in cancer: not a single cell alike
Cell Immunol 330, 188-201, 2018. (Epub 2018 Feb 14)

Movahedi, K, Wiegmann, R, De Vlaminck, K, Van Ginderachter, JA, Nikolaev, VO.
RoMo: An efficient strategy for functional mosaic analysis via stochastic Cre recombination and gene targeting in the ROSA26 locus
Biotechnol Bioeng 115, 1778-1792, 2018. (Epub 2018 Mar 24)

Nuhn, L, Bolli, E, Massa, S, Vandenberghe, I, Movahedi, K, Devreese, B, Van Ginderachter, J, De Geest, BG.
Targeting protumoral tumor-associated macrophages with nanobody-functionalized nanogels through SPAAC ligation
Bioconjug Chem 29, 2394-2405, 2018. (Epub 2018 Jun 11)

Raaymakers, C, Verbrugghe, E, Stijlemans, B, Martel, A, Pasmans, F, Roelants, K.
The anuran skin peptide bradykinin mediates its own absorption across epithelial barriers of the digestive tract
Peptides 103, 84-89, 2018. (Epub 2018 Mar 20)

Rizzolio, S, Cagnoni, G, Battistini, C, Bonelli, S, Isella, C, Van Ginderachter, JA, Bernards, R, Di Nicolantonio, F, Giordano, S, Tamagnone, L.
Neuropilin-1 upregulation elicits adaptive resistance to oncogene-targeted therapies
J Clin Invest 128, 3976-3990, 2018. (Epub 2018 Jun 28)

Ronca, R, Van Ginderachter, JA, Turtoi, A.
Paracrine interactions of cancer-associated fibroblasts, macrophages and endothelial cells: tumor allies and foes
Curr Opin Oncol 30, 4553, 2018. (Epub 2017 Oct 27)

Scott, CL, T'Jonck, W, Martens, L, Todorov, H, Sichien, D, Soen, B, Bonnardel, J, De Prijck, S, Vandamme, N, Cannoodt, R, Saelens, W, Vanneste, B, Toussaint, W, De Bleser, P, Takahashi, N, Vandenabeele, P, et al., Lambrecht, BN, De Baetselier, P, Milling, SWF, Van Ginderachter, JA, Malissen, B, Berx, G, Beschin, A, Saeys, Y, Guilliams, M.
The Transcription Factor ZEB2 Is Required to Maintain the Tissue-Specific Identities of Macrophages
Immunity 49, 312-325, 2018. (Epub 2018 Jul 31)

Senders, ML, Hernot, S, Carlucci, G, van de Voort, JC, Fay, F, Calcagno, C, Tang, J, Alaarg, A, Zhao, Y, Ishino, S, Palmisano, A, Boeykens, G, Meerwaldt, AE, Sanchez-Gaytan, BL, Baxter, S, Zendman, L, Lobatto, ME, et al., Raes, G, et al..
Nanobody-Facilitated Multiparametric PET/MRI Phenotyping of Atherosclerosis
JACC Cardiovasc Imaging , in press, 2018. (Epub 2018 Oct 12)

Sharma, PK, Dmitriev, IP, Kashentseva, EA, Raes, G, Li, L, Kim, SW, Lu, ZH, Arbeit, JM, Fleming, TP, Kaliberov, SA, Goedegebuure, SP, Curiel, DT, Gillanders, WE.
Development of an adenovirus vector vaccine platform for targeting dendritic cells
Cancer Gene Ther 25, 1-2, 2018. (Epub 2017 Dec 15)

Sparkes, A, De Baetselier, P, Brys, L, Cabrito, I, Sterckx, YG, Schoonooghe, S, Muyldermans, S, Raes, G, Bucala, R, Vanlandschoot, P, Van Ginderachter, JA, Stijlemans, B.
Novel half-life extended anti-MIF nanobodies protect against endotoxic shock
FASEB J 32, 3411-3422, 2018. (Epub 2018 Jan 25)

Spiranec, K, Chen, W, Werner, F, Nikolaev, VO, Naruke, T, Koch, F, Werner, A, Eder-Negrin, P, Dieguez-Hurtado, R, Adams, RH, Baba, HA, Schmidt, H, Schuh, K, Skryabin, BV, Movahedi, K, Schweda, F, Kuhn, M.
Endothelial C-Type Natriuretic Peptide Acts on Pericytes to Regulate Microcirculatory Flow and Blood Pressure
Circulation 138, 494-508, 2018. (Epub 2018 Jul 31)

Stijlemans, B, De Baetselier, P, Magez, S, Van Ginderachter, JA, De Trez, C.
African Trypanosomiasis-Associated Anemia: The Contribution of the Interplay between Parasites and the Mononuclear Phagocyte System
Frontiers in Immunology , 9, 2018. (Epub 2018 Feb 15)

Bolli, E, Movahedi, K, Laoui, D, Van Ginderachter, JA.
Novel insights in the regulation and function of macrophages in the tumor microenvironment
Curr Opin Oncol 29, 55-61, 2017. (Epub 2016 Oct 26)

Broos, K, Keyaerts, M, Lecocq, Q, Renmans, D, Nguyen, T, Escors, D, Liston, A, Raes, G, Breckpot, K, Devoogdt, N.
Non-invasive assessment of murine PD-L1 levels in syngeneic tumor models by nuclear imaging with nanobody tracers
Oncotarget 8, 41932-41946, 2017. (Epub 2017 Jun 27)

Cleeren, F, Lecina, J, Ahamed, M, Raes, G, Devoogdt, N, Caveliers, V, McQuade, P, Rubins, DJ, Li, W, Verbruggen, A, Xavier, C, Bormans, G.
Al(18)F-Labeling Of Heat-Sensitive Biomolecules for Positron Emission Tomography Imaging
Theranostics 7, 2924-2939, 2017. (Epub 2017 Jul 14)

De Beule, N, De Veirman, K, Maes, K, De Bruyne, E, Menu, E, Breckpot, K, De Raeve, H, Van Rampelbergh, R, Van Ginderachter, JA, Schots, R, Van Valckenborgh, E, Vanderkerken, K.
Tumor-associated macrophage-mediated survival of myeloma cells through STAT3 activation
J Pathol 241, 534-546, 2017. (Epub 2016 Dec 15)

D'Huyvetter, M, De Vos, J, Xavier, C, Pruszynski, M, Sterckx, YGJ, Massa, S, Raes, G, Caveliers, V, Zalutsky, MR, Lahoutte, T, Devoogdt, N.
(131)I-labeled Anti-HER2 Camelid sdAb as a Theranostic Tool in Cancer Treatment
Clin Cancer Res 23, 6616-6628, 2017. (Epub 2017 Nov 1)

Farro, G, Stakenborg, M, Gomez-Pinilla, PJ, Labeeuw, E, Goverse, G, Giovangiulio, MD, Stakenborg, N, Meroni, E, D'Errico, F, Elkrim, Y, Laoui, D, Lisowski, ZM, Sauter, KA, Hume, DA, Van Ginderachter, JA, Boeckxstaens, GE, Matteoli, G.
CCR2-dependent monocyte-derived macrophages resolve inflammation and restore gut motility in postoperative ileus
Gut 66, 2098-2109, 2017. (Epub 2017 Jun 14)

Geeraerts, X, Bolli, E, Fendt, SM, Van Ginderachter, JA.
Macrophage Metabolism As Therapeutic Target for Cancer, Atherosclerosis, and Obesity
Front Immunol 8, 289, 2017. (Epub 2017 Mar 15)

Goyvaerts, C, De Vlaeminck, Y, Escors, D, Lienenklaus, S, Keyaerts, M, Raes, G, Breckpot, K.
Antigen-presenting cell-targeted lentiviral vectors do not support the development of productive T-cell effector responses: implications for in vivo targeted vaccine delivery
Gene Ther 24, 370-375, 2017. (Epub 2017 May 25)

Keirsse, J, Van Damme, H, Van Ginderachter, JA, Laoui, D.
Exploiting tumor-associated dendritic cell heterogeneity for novel cancer therapies
J Leukoc Biol 102, 317-324, 2017. (Epub 2017 Apr)

Korf, H, Breser, L, Van Hoeck, J, Godoy, J, Cook, DP, Stijlemans, B, De Smidt, E, Moyson, C, Monteiro Carvalho Mori Cunha, JP, Rivero, V, Gysemans, C, Mathieu, C.
MIF inhibition interferes with the inflammatory and T cell-stimulatory capacity of NOD macrophages and delays autoimmune diabetes onset
PLoS One 12, e0187455, 2017. (Epub 2017 Nov 2)

Maes, M, McGill, MR, da Silva, TC, Abels, C, Lebofsky, M, Weemhoff, JL, Tiburcio, T, Veloso Alves Pereira, I, Willebrords, J, Crespo Yanguas, S, Farhood, A, Beschin, A, Van Ginderachter, JA, Penuela, S, Jaeschke, H, Cogliati, B, Vinken, M.
Inhibition of pannexin1 channels alleviates acetaminophen-induced hepatotoxicity
Arch Toxicol 91, 2263-2264, 2017. (Epub 2016 Nov 8)

Nzoumbou-Boko, R, De Muylder, G, Semballa, S, Lecordier, L, Dauchy, FA, Gobert, AP, Holzmuller, P, Lemesre, JL, Bras-Goncalves, R, Barnabe, C, Courtois, P, Daulouede, S, Beschin, A, Pays, E, Vincendeau, P.
Trypanosoma musculi Infection in Mice Critically Relies on Mannose Receptor-Mediated Arginase Induction by a TbKHC1 Kinesin H Chain Homolog
J Immunol 199, 1762-1771, 2017. (Epub 2017 Sep 1)

Sparkes, A, De Baetselier, P, Roelants, K, De Trez, C, Magez, S, Van Ginderachter, JA, Raes, G, Bucala, R, Stijlemans, B.
Reprint of: The non-mammalian MIF superfamily
Immunobiology 222, 858-867, 2017. (Epub 2017 May 30)

Sparkes, A, De Baetselier, P, Roelants, K, De Trez, C, Magez, S, Van Ginderachter, JA, Raes, G, Bucala, R, Stijlemans, B.
The non-mammalian MIF superfamily
Immunobiology 222, 473-482, 2017. (Epub 2016 Oct 12)

Stijlemans, B, De Baetselier, P, Caljon, G, Van Den Abbeele, J, Van Ginderachter, JA, Magez, S.
Nanobodies As Tools to Understand, Diagnose, and Treat African Trypanosomiasis
Front Immunol 8, 724, 2017. (Epub 2017 Jun 30)

Stijlemans, B, Radwanska, M, De Trez, C, Magez, S.
African Trypanosomes Undermine Humoral Responses and Vaccine Development: Link with Inflammatory Responses?
Front Immunol 8, 582, 2017. (Epub 2017 May 24)

Vandereyken, M, Jacques, S, Van Overmeire, E, Amand, M, Rocks, N, Delierneux, C, Singh, P, Singh, M, Ghuysen, C, Wathieu, C, Zurashvili, T, Sounni, NE, Moutschen, M, Gilles, C, Oury, C, Cataldo, D, Van Ginderachter, JA, Rahmouni, S.
Dusp3 deletion in mice promotes experimental lung tumour metastasis in a macrophage dependent manner
PLoS One 12, e0185786, 2017. (Epub 2017 Oct 11)

Vanwalleghem, G, Morias, Y, Beschin, A, Szymkowski, DE, Pays, E.
Trypanosoma brucei growth control by TNF in mammalian host is independent of the soluble form of the cytokine
Sci Rep 7, 6165, 2017. (Epub 2017 Jul 21)

Wen, Y, Ouyang, Z, Schoonooghe, S, Luo, S, De Baetselier, P, Lu, W, Muyldermans, S, Raes, G, Zheng, F.
Structural evaluation of a nanobody targeting complement receptor Vsig4 and its cross reactivity
Immunobiology 222, 807-813, 2017. (Epub 2016 Nov 16)

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