» Home » Research 
Print this pageEmail this page URLConvert this page to PDF

Publications by this IRC author

(Publications from the same author but with another affiliation than IRC cannot be displayed here)

For copyright reasons, PDF-versions of our publications are available on the intranet only (login required  ). If you would like to receive a reprint of an IRC paper, please copy/paste the reference in the
reprint request form 


Click the UGent logo to retrieve publications of Tino Hochepied in the UGent bibliography

Gurumurthy, CB, O'Brien, AR, Quadros, RM, Adams, J, Jr., Alcaide, P, Ayabe, S, Ballard, J, Batra, SK, Beauchamp, MC, Becker, KA, Bernas, G, Brough, D, Carrillo-Salinas, F, Chan, W, Chen, H, Dawson, R, DeMambro, V, D'Hont, J, Dibb, K, et al..
Response to correspondence on "Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation"
Genome Biol 22, 99, 2021. (Epub 2021 Apr 7)

Hoste, E, Lecomte, K, Annusver, K, Vandamme, N, Roels, J, Maschalidi, S, Verboom, L, Vikkula, HK, Sze, M, Van Hove, L, Verstaen, K, Martens, A, Hochepied, T, Saeys, Y, Ravichandran, K, Kasper, M, van Loo, G.
OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity
Nat Commun 12, 5913, 2021. (Epub 2021 Oct 8)

Van Hove, L, Lecomte, K, Roels, J, Vandamme, N, Vikkula, HK, Hoorens, I, Ongenae, K, Hochepied, T, Donati, G, Saeys, Y, Quist, SR, Watt, FM, van Loo, G, Hoste, E.
Fibrotic enzymes modulate wound-induced skin tumorigenesis
EMBO Rep , e51573, 2021. (Epub 2021 Mar 29)

Martens, A, Priem, D, Hoste, E, Vetters, J, Rennen, S, Catrysse, L, Voet, S, Deelen, L, Sze, M, Vikkula, H, Slowicka, K, Hochepied, T, Iliaki, K, Wullaert, A, Janssens, S, Lamkanfi, M, Beyaert, R, Armaka, M, Bertrand, MJM, et al..
Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities
Nat Immunol 21, 381-387, 2020. (Epub 2020 Mar 16)

Van Nuffel, E, Staal, J, Baudelet, G, Haegman, M, Driege, Y, Hochepied, T, Afonina, IS, Beyaert, R.
MALT1 targeting suppresses CARD14-induced psoriatic dermatitis in mice
EMBO Rep 21, e49237, 2020. (Epub 2020 Apr 28)

Andries, V, De Keuckelaere, E, Staes, K, Hochepied, T, Taminau, J, Lemeire, K, Birembaut, P, Berx, G, van Roy, F.
A new mouse model to study the role of ectopic Nanos3 expression in cancer
BMC Cancer 19, 598, 2019. (Epub 2019 Jun 17)

Demeyer, A, Skordos, I, Driege, Y, Kreike, M, Hochepied, T, Baens, M, Staal, J, Beyaert, R.
MALT1 Proteolytic Activity Suppresses Autoimmunity in a T Cell Intrinsic Manner
Front Immunol 10, 1898, 2019. (Epub 2019 Aug 14)

Gurumurthy, CB, O'Brien, AR, Quadros, RM, Adams, J, Jr., Alcaide, P, Ayabe, S, Ballard, J, Batra, SK, Beauchamp, MC, Becker, KA, Bernas, G, Brough, D, Carrillo-Salinas, F, Chan, W, Chen, H, Dawson, R, DeMambro, V, D'Hont, J, Dibb, KM, et al..
Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation
Genome Biol 20, 171, 2019. (Epub 2019 Aug 26)

Pieters, T, T'Sas, S, Demoen, L, Almeida, A, Haenebalcke, L, Matthijssens, F, Lemeire, K, D'Hont, J, Van Rockeghem, F, Hochepied, T, Lintermans, B, Reunes, L, Lammens, T, Berx, G, Haigh, JJ, Goossens, S, Van Vlierberghe, P.
Novel strategy for rapid functional in vivo validation of oncogenic drivers in haematological malignancies
Sci Rep 9, 10577, 2019. (Epub 2019 Jul 22)

Bouhy, D, Juneja, M, Katona, I, Holmgren, A, Asselbergh, B, De Winter, V, Hochepied, T, Goossens, S, Haigh, JJ, Libert, C, Ceuterick-de Groote, C, Irobi, J, Weis, J, Timmerman, V.
A knock-in/knock-out mouse model of HSPB8-associated distal hereditary motor neuropathy and myopathy reveals toxic gain-of-function of mutant Hspb8
Acta Neuropathol 135, 131-148, 2018. (Epub 2017 Aug 5)

De Clercq, S, Keruzore, M, Desmaris, E, Pollart, C, Assimacopoulos, S, Preillon, J, Ascenzo, S, Matson, CK, Lee, M, Nan, X, Li, M, Nakagawa, Y, Hochepied, T, Zarkower, D, Grove, EA, Bellefroid, EJ.
DMRT5 Together with DMRT3 Directly Controls Hippocampus Development and Neocortical Area Map Formation
Cereb Cortex 28, 493-509, 2018. (Epub 2016 Dec 27)

Lazzarano, S, Kucka, M, Castro, JPL, Naumann, R, Medina, P, Fletcher, MNC, Wombacher, R, Gribnau, J, Hochepied, T, Van Montagu, M, Libert, C, Chan, YF.
Genetic mapping of species differences via in vitro crosses in mouse embryonic stem cells
Proc Natl Acad Sci U S A 115, 3680-3685, 2018. (Epub 2018 Mar 21)

Devos, M, Gilbert, B, Denecker, G, Leurs, K, Mc Guire, C, Lemeire, K, Hochepied, T, Vuylsteke, M, Lambert, J, Van Den Broecke, C, Libbrecht, L, Haigh, J, Berx, G, Lippens, S, Vandenabeele, P, Declercq, W.
Elevated DeltaNp63alpha levels facilitate epidermal and biliary oncogenic transformation
J Invest Dermatol 137, 494-505, 2017. (Epub 2016 Oct 7)

Pieters, T, Haenebalcke, L, Bruneel, K, Vandamme, N, Hochepied, T, van Hengel, J, Wirth, D, Berx, G, Haigh, JJ, van Roy, F, Goossens, S.
Structure-function Studies in Mouse Embryonic Stem Cells Using Recombinase-mediated Cassette Exchange
J Vis Exp , 122, 2017. (Epub 2017 Apr 27)

Van Opdenbosch, N, Van Gorp, H, Verdonckt, M, Saavedra, PHV, de Vasconcelos, NM, Goncalves, A, Vande Walle, L, Demon, D, Matusiak, M, Van Hauwermeiren, F, D'Hont, J, Hochepied, T, Krautwald, S, Kanneganti, TD, Lamkanfi, M.
Caspase-1 Engagement and TLR-Induced c-FLIP Expression Suppress ASC/Caspase-8-Dependent Apoptosis by Inflammasome Sensors NLRP1b and NLRC4
Cell Rep 21, 3427-3444, 2017. (Epub 2017 Dec 19)

Bouhy, D, Geuens, T, De Winter, V, Almeida-Souza, L, Katona, I, Weis, J, Hochepied, T, Goossens, S, Haigh, J, Janssens, S, Timmerman, V.
Characterization of New Transgenic Mouse Models for Two Charcot-Marie-Tooth-Causing HspB1 Mutations using the Rosa26 Locus
Journal of Neuromuscular Diseases 3, 183-200, 2016. (Epub 2016 May 27)

Carceller, E, Ballegeer, M, Deckers, J, Riccardi, C, Bruscoli, S, Hochepied, T, Libert, C, Perez, P.
Overexpression of Glucocorticoid-induced Leucine Zipper (GILZ) increases susceptibility to Imiquimod-induced psoriasis and involves cutaneous activation of TGF-beta1
Sci Rep 6, 38825, 2016. (Epub 2016 Dec 9)

Kuchmiy, AA, D'Hont, J, Hochepied, T, Lamkanfi, M.
NLRP2 controls age-associated maternal fertility
J Exp Med 213, 2851-2860, 2016. (Epub 2016 Nov 23)

Pieters, T, Goossens, S, Haenebalcke, L, Andries, V, Stryjewska, A, De Rycke, R, Lemeire, K, Hochepied, T, Huylebroeck, D, Berx, G, Stemmler, MP, Wirth, D, Haigh, JJ, van Hengel, J, van Roy, F.
p120 Catenin-Mediated Stabilization of E-Cadherin Is Essential for Primitive Endoderm Specification
PLoS Genet 12, e1006243, 2016. (Epub 2016 Aug 24)

Van Gorp, H, Saavedra, PH, de Vasconcelos, NM, Van Opdenbosch, N, Vande Walle, L, Matusiak, M, Prencipe, G, Insalaco, A, Van Hauwermeiren, F, Demon, D, Bogaert, DJ, Dullaers, M, De Baere, E, Hochepied, T, Dehoorne, J, Vermaelen, KY, Haerynck, F, De Benedetti, F, Lamkanfi, M.
Familial Mediterranean fever mutations lift the obligatory requirement for microtubules in Pyrin inflammasome activation
Proc Natl Acad Sci U S A 113, 14384-14389, 2016. (Epub 2016 Nov 22)

Thoonen, R, Cauwels, A, Decaluwe, K, Geschka, S, Tainsh, RE, Delanghe, J, Hochepied, T, De Cauwer, L, Rogge, E, Voet, S, Sips, P, Karas, RH, Bloch, KD, Vuylsteke, M, Stasch, JP, Van de Voorde, J, Buys, ES, Brouckaert, P.
Cardiovascular and pharmacological implications of haem-deficient NO-unresponsive soluble guanylate cyclase knock-in mice
Nat Commun 6, 8482, 2015. (Epub 2015 Oct 7)

Van Overbeke, W, Wongsantichon, J, Everaert, I, Verhelle, A, Zwaenepoel, O, Loonchanta, A, Burtnick, LD, De Ganck, A, Hochepied, T, Haigh, J, Cuvelier, C, Derave, W, Robinson, RC, Gettemans, J.
An ER-directed gelsolin nanobody targets the first step in amyloid formation in a gelsolin amyloidosis mouse model
Hum Mol Genet 24, 2492-507, 2015. (Epub 2015 May 1)

Haenebalcke, L, Goossens, S, Dierickx, P, Bartunkova, S, D'Hont, J, Haigh, K, Hochepied, T, Wirth, D, Nagy, A, Haigh, JJ.
The ROSA26-iPSC mouse: A conditional, inducible and exchangeable resource for studying cellular (de)differentiation
Cell Reports 3, 335-341, 2013. (Epub 2013 Feb 5)

Vanhooren, V, Vandenbroucke, RE, Dewaele, S, Van Hamme, E, Haigh, J, Hochepied, T, Libert, C.
Mice overexpressing beta-1,4-galactosyltransferase I are resistant to TNF-induced inflammation and DSS-induced colitis
PLoS One 8, e79883, 2013. (Epub 2013 Dec 5)

Vyas, R, Kumar, R, Clermont, F, Helfricht, A, Kalev, P, Sotiropoulou, P, Hendriks, IA, Radaelli, E, Hochepied, T, Blanpain, C, Sablina, A, van Attikum, H, Olsen, JV, Jochemsen, AG, Vertegaal, ACO, Marine, JC.
RNF4 is required for DNA double-strand break repair in vivo
Cell Death Differ 20, 490-502, 2013. (Epub 2012 Nov 30)

Pieters, T, Haenebalcke, L, Hochepied, T, D'Hont, J, Haigh, JJ, van Roy, F, van Hengel, J.
Efficient and user-friendly pluripotin-based derivation of mouse embryonic stem cells
Stem Cell Rev Rep 8, 768-778, 2012. (Epub 2011 Oct 20)

Migliorini, D, Bogaerts, S, Defever, D, Vyas, R, Denecker, G, Radaelli, E, Zwolinska, A, Depaepe, V, Hochepied, T, Skarnes, WC, Marine, JC.
Cop1 constitutively regulates c-Jun protein stability and functions as a tumor suppressor in mice
J Clin Invest 121, 1329-1343, 2011. (Epub 2011 Mar 14)

Denecker, G, Hoste, E, Gilbert, B, Hochepied, T, Ovaere, P, Lippens, S, Van den Broecke, C, Van Damme, P, D'Herde, K, Hachem, J-P, Borgonie, G, Presland, RB, Schoonjans, L, Libert, C, Vandekerckhove, J, Gevaert, K, Vandenabeele, P, Declercq, W.
Caspase-14 protects against epidermal UVB photo-damage and water loss
Nature Cell Biol 9, 666-674, 2007. (Epub 2007 May 21)

Mahieu, T, Park, JM, Revets, H, Pasche, B, Lengeling, A, Staelens, S, Wullaert, A, Vanlaere, I, Hochepied, T, Van Roy, F, Karin, M, Libert, C.
The wild-derived inbred mouse strain SPRET/Ei is resistant to LPS and defective in IFN-beta production
Proc Natl Acad Sci USA 103, 2292-2297, 2006. (Epub 2006 Feb 2)

de Vries, B, Walter, S, Wolfs, T, Hochepied, T, Rabina, J, Heeringa, P, Parkkinen, J, Libert, C, Buurman, W.
Exogenous alpha-1-acid glycoprotein protects against renal ischemia-reperfusion injury by inhibition of inflammation and apoptosis.
Transplantation 78, 1116-1124, 2004. (Epub ---)

Hochepied, T, Schoonjans, L, Staelens, J, Kreemers, V, Danloy, S, Puimège, L, Collen, D, Van Roy, F, Libert, C.
Breaking the species barrier: derivation of germline-competent embryonic stem cells from Mus spretus x C57BL/6 hybrids
Stem Cells 22, 441-447, 2004. (Epub ---)

Staelens, J, Puimège, L, Mahieu, T, Pynaert, G, Hochepied, T, Vandenabeele, A, Grooten, J, Kontoyiannis, D, Van Roy, F, Kollias, G, Libert, C.
Response of TNF-hyporesponsive SPRET/Ei mice in models of inflammatory disorders
Mamm Genome 15, 537-543, 2004. (Epub ---)

Hochepied, T, Berger, FG, Baumann, H, Libert, C.
a1-Acid glycoprotein: An acute phase protein with inflammatory and immunomodulating properties
Cytokine Growth Factor Rev 14, 25-34, 2003. (Epub ---)

Hochepied, T, Van Leuven, F, Libert, C.
Mice lacking a2-macroglobulin show an increased host defence against Gram-negative bacterial sepsis, but are more susceptible to endotoxic shock
Eur Cytokine Netw 13, 86-91, 2002. (Epub ---)

Hochepied, T, Wullaert, A, Berger, FG, Baumann, H, Brouckaert, P, Steidler, L, Libert, C.
Overexpression of a1-acid glycoprotein in transgenic mice leads to sensitisation to acute colitis
Gut 51, 398-404, 2002. (Epub ---)

Wielockx, B, Hochepied, T, Staelens, J, Van Molle, W, Brouckaert, P, Libert, C.
Detection, characterisation and purification of a murine liver factor capable of desensitising towards the lethal activity of tumour necrosis factor
Cytokine 15, 59-65, 2001. (Epub ---)

Hochepied, T, Ameloot, P, Brouckaert, P, Van Leuven, F, Libert, C.
Differential response of a2-macroglobulin-deficient mice in models of lethal TNF-induced inflammation
Eur Cytokine Netw 11, 597-601, 2000. (Epub ---)

Hochepied, T, Van Molle, W, Berger, FG, Baumann, H, Libert, C.
Involvement of the acute phase protein a1-acid glycoprotein in nonspecific resistance to a lethal Gram-negative infection
J Biol Chem 275, 14903-14909, 2000. (Epub ---)

Van Molle, W, Hochepied, T, Brouckaert, P, Libert, C.
The major acute-phase protein, serum amyloid P component, in mice is not involved in endogenous resistance against tumor necrosis factor alpha-induced lethal hepatitis, shock, and skin necrosis
Infect Immun 68, 5026-5029, 2000. (Epub ---)

Libert, C, Hochepied, T, Berger, FG, Baumann, H, Fiers, W, Brouckaert, P.
High-level constitutive expression of a1-acid glycoprotein and lack of protection against tumor necrosis factor-induced lethal shock in transgenic mice
Transgenic Res 7, 429-435, 1998. (Epub ---)

Back to previous page

Export in CSV

To top

What do these icons mean?

pdf file (800 kb)