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Selected IRC publications
The IRC publications that match your query are listed below.
For copyright reasons, PDF-versions of our publications are available on the intranet only (login required 
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Eelen, G, Dubois, C, Cantelmo, AR, Goveia, J, Bruning, U, DeRan, M, Jarugumilli, G, van Rijssel, J, Saladino, G, Comitani, F, Zecchin, A, Rocha, S, Chen, R, Huang, H, Vandekeere, S, Kalucka, J, Lange, C, et al., Haustraete, J, et al. Role of glutamine synthetase in angiogenesis beyond glutamine synthesis Nature 561, 63-69, 2018. (Epub 2018 Aug 29) 
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El Ashkar, S, Schwaller, J, Pieters, T, Goossens, S, Demeulemeester, J, Christ, F, Van Belle, S, Juge, S, Boeckx, N, Engelman, A, Van Vlierberghe, P, Debyser, Z, De Rijck, J. LEDGF/p75 is dispensable for hematopoiesis but essential for MLL-rearranged leukemogenesis Blood 131, 95-107, 2018. (Epub 2017 Oct 30)
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Estornes, Y, Dondelinger, Y, Weber, K, Bruggeman, I, Peall, A, MacFarlane, M, Lebecque, S, Vandenabeele, P, Bertrand, MJM. N-glycosylation of mouse TRAIL-R restrains TRAIL-induced apoptosis Cell Death Dis 9, 494, 2018. (Epub 2018 May 2)
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Facchini, FA, Zaffaroni, L, Minotti, A, Rapisarda, S, Calabrese, V, Forcella, M, Fusi, P, Airoldi, C, Ciaramelli, C, Billod, JM, Schromm, A, Braun, H, Palmer, C, Beyaert, R, Lapenta, F, Jerala, R, Pirianov, G, Martin-Santamaria, S, Peri, F. Structure-Activity Relationship in Monosaccharide-Based Toll-Like Receptor 4 (TLR4) Antagonists J Med Chem 61, 2895-2909, 2018. (Epub 2018 Mar 12)
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Flores-Langarica, A, Cook, C, Muller Luda, K, Persson, EK, Marshall, JL, Beristain-Covarrubias, N, Yam-Puc, JC, Dahlgren, M, Persson, JJ, Uematsu, S, Akira, S, Henderson, IR, Lindbom, BJ, Agace, W, Cunningham, AF. Intestinal CD103(+)CD11b(+) cDC2 Conventional Dendritic Cells Are Required for Primary CD4(+) T and B Cell Responses to Soluble Flagellin Front Immunol 9, 2409, 2018. (Epub 2018 Oct 17)
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Fulara, A, Vandenberghe, I, Read, RJ, Devreese, B, Savvides, SN. Structure and oligomerization of the periplasmic domain of GspL from the type II secretion system of Pseudomonas aeruginosa Sci Rep 8, 16760, 2018. (Epub 2018 Nov 13)
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Galluzzi, L, Vitale, I, Aaronson, SA, Abrams, JM, Adam, D, Agostinis, P, Alnemri, ES, et al., Bertrand, MJM, et al., Vanden Berghe, T, Vandenabeele, P, et al., Kroemer,G. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 Cell Death Differ 25, 486-541, 2018. (Epub 2018 Jan 23)
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Gao, Z, Daneva, A, Salanenka, Y, Van Durme, M, Huysmans, M, Lin, Z, De Winter, F, Vanneste, S, Karimi, M, Van de Velde, J, Vandepoele, K, Van de Walle, C, Dewettinck, K, Lambrecht, BN, Nowack, MK. KIRA1 and ORESARA1 terminate flower receptivity by promoting cell death in the stigma of Arabidopsis Nature Plants 4, 365–375 , 2018. (Epub 2018 May 28)
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Geric, I, Tyurina, YY, Krysko, O, Krysko, DV, De Schryver, E, Kagan, VE, Van Veldhoven, PP, Baes, M, Verheijden, S. Lipid homeostasis and inflammatory activation are disturbed in classically activated macrophages with peroxisomal beta-oxidation deficiency Immunology 153, 342-356, 2018. (Epub 2017 Sep 22)
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Gilis, E, Mortier, C, Venken, K, Debusschere, K, Vereecke, L, Elewaut, D. The Role of the Microbiome in Gut and Joint Inflammation in Psoriatic Arthritis and Spondyloarthritis J Rheumatol Suppl 94, 36-39, 2018. (Epub 2018 Jun)
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Ginhoux, F, Guilliams, M. Editorial for Cellular Immunology special issue on "Tissue Macrophages" Cell Immunol 330, 1-4, 2018. (Epub 2018 Aug 18)
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Godar, M, Blanchetot, C, de Haard, H, Lambrecht, BN, Brusselle, G. Personalized medicine with biologics for severe type 2 asthma: current status and future prospects MAbs 10, 34-45, 2018. (Epub 2017 Oct 16)
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Godar, M, de Haard, H, Blanchetot, C, Rasser, J. Therapeutic bispecific antibody formats: a patent applications review (1994-2017) Expert Opin Ther Pat 28, 251-276, 2018. (Epub 2018 Jan 25)
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Godar, M, Deswarte, K, Vergote, K, Saunders, M, de Haard, H, Hammad, H, Blanchetot, C, Lambrecht, BN. A bispecific antibody strategy to target multiple type 2 cytokines in asthma J Allergy Clin Immunol 142, 1185-1193, 2018. (Epub 2018 Jun 8)
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Gorle, N, Blaecher, C, Bauwens, E, Vandendriessche, C, Balusu, S, Vandewalle, J, Van Cauwenberghe, C, Van Wonterghem, E, Van Imschoot, G, Liu, C, Ducatelle, R, Libert, C, Haesebrouck, F, Smet, A, Vandenbroucke, RE. The choroid plexus epithelium as a novel player in the stomach-brain axis during Helicobacter infection Brain Behav Immun 69, 35-47, 2018. (Epub 2017 Dec 16)
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Govindarajan, S, Gaublomme, D, Van der Cruyssen, R, Verheugen, E, Van Gassen, S, Saeys, Y, Tavernier, S, Iwawaki, T, Bloch, Y, Savvides, SN, Lambrecht, BN, Janssens, S, Elewaut, D, Drennan, MB. Stabilization of cytokine mRNAs in iNKT cells requires the serine-threonine kinase IRE1alpha Nat Commun 9, 5340, 2018. (Epub 2018 Dec 17)
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Guilliams, M, Mildner, A, Yona, S. Developmental and Functional Heterogeneity of Monocytes Immunity 49, 595-613, 2018. (Epub 2018 Oct 16)
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Guilliams, M, Scott, CL. 'NOTCHing up' the In Vitro Production of Dendritic Cells Trends Immunol 39, 765-767, 2018. (Epub 2018 Aug 24)
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Gul, IS, Staal, J, Hulpiau, P, De Keuckelaere, E, Kamm, K, Deroo, T, Sanders, E, Staes, K, Driege, Y, Saeys, Y, Beyaert, R, Technau, U, Schierwater, B, Van Roy, F. GC content of early metazoan genes and its impact on gene expression levels in mammalian cell lines Genome biology and Evolution 10, 909–917, 2018. (Epub 2018 Feb 21)
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Haspeslagh, E, Heyndrickx, I, Hammad, H, Lambrecht, BN. The hygiene hypothesis: immunological mechanisms of airway tolerance Curr Opin Immunol 54, 102-108, 2018. (Epub 2018 Jul 6)
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Haspeslagh, E, van Helden, MJ, Deswarte, K, De Prijck, S, van Moorleghem, J, Boon, L, Hammad, H, Vivier, E, Lambrecht, BN. Role of NKp46(+) natural killer cells in house dust mite-driven asthma EMBO Mol Med 10, UNSP e8657, 2018. (Epub 2018 Feb 14)
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Hassannia, B, Wiernicki, B, Ingold, I, Qu, F, Van Herck, S, Tyurina, YY, Bayir, H, Abhari, BA, Angeli, JPF, Choi, SM, Meul, E, Heyninck, K, et al., Lahtela-Kakkonen, M, Van Camp, G, Krysko, DV, Ekert, PG, Fulda, S,De Geest, B.G., Vanden Berghe, W., Vandenabeele, P., Vanden Berghe, T. Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma J Clin Invest 128, 3341-3355, 2018. (Epub 2018 Jun 25)
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Hofmans, S, Devisscher, L, Martens, S, Van Rompaey, D, Goossens, K, Divert, T, Nerinckx, W, Takahashi, N, De Winter, H, Van der Veken, P, Goossens, V, Vandenabeele, P, Augustyns, K. Tozasertib analogues as inhibitors of necroptotic cell death J Med Chem 61, 1895-1920, 2018. (Epub 2018 Feb 13)
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Hoste, L, De Baets, F, Van Daele, S, Schelstraete, P, Boon, M, De Bruyne, M, Dullaers, M, Coppieters, F, Haerynck, F. When One Rare Disease Hides Another: Kartagener Syndrome Masking FMF Clin Pediatr (Phila) 57, 981-985, 2018. (Epub 2017 Sep 1)
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Imbrechts, M, De Samblancx, K, Fierens, K, Brisse, E, Vandenhaute, J, Mitera, T, Libert, C, Smets, I, Goris, A, Wouters, C, Matthys, P. IFN-gamma stimulates CpG-induced IL-10 production in B cells via p38 and JNK signalling pathways Eur J Immunol 48, 1506-1521, 2018. (Epub 2018 Jul 13)
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Izquierdo, HM, Brandi, P, Gomez, MJ, Conde-Garrosa, R, Priego, E, Enamorado, M, Martinez-Cano, S, Sanchez, I, Conejero, L, Jimenez-Carretero, D, Martin-Puig, S, Guilliams, M, Sancho, D. Von Hippel-Lindau Protein Is Required for Optimal Alveolar Macrophage Terminal Differentiation, Self-Renewal, and Function Cell Rep 24, 1738-1746, 2018. (Epub 2018 Aug 14)
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Jans, L, De Kock, I, Herregods, N, Verstraete, K, Van den Bosch, F, Carron, P, Oei, EH, Elewaut, D, Jacques, P. Dual-energy CT: a new imaging modality for bone marrow oedema in rheumatoid arthritis Ann Rheum Dis 77, 958-959, 2018. (Epub 2018 Mar 1)
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Kania, U, Nodzynski, T, Lu, Q, Hicks, GR, Nerinckx, W, Mishev, K, Peurois, F, Cherfils, J, De Rycke, RM, Grones, P, Robert, S, Russinova, E, Friml, J. Endosidin 4 inhibitor targets the SEC7 domain-type ARF-GEFs and interferes with subcellular trafficking in eukaryotes Plant Cell 30, 2553-2572, 2018. (Epub 2018 Jul 17)
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Kanneganti, A, Malireddi, RKS, Saavedra, PHV, Vande Walle, L, Van Gorp, H, Kambara, H, Tillman, H, Vogel, P, Luo, HR, Xavier, RJ, Chi, H, Lamkanfi, M. GSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever J Exp Med 215, 1519-1529, 2018. (Epub 2018 Jun 4)
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Kauffmann, F, Meert, E, de Jonge, K, Elkrim, Y, Hanot Mambres, D, Denis, O, Muraille, E, Magez, S, De Trez, C. STAT6 Mediates Footpad Immunopathology in the Absence of IL-12p40 Following Infection of Susceptible BALB/c Mice With Leishmania major Front Immunol 9, 503, 2018. (Epub 2018 Mar 14)
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Keirsse, J, Van Damme, H, Geeraerts, X, Beschin, A, Raes, G, Van Ginderachter, JA. The role of hepatic macrophages in liver metastasis Cell Immunol 330, 202-215, 2018. (Epub 2018 Apr 6)
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Kiltz, U, van der Heijde, D, Boonen, A, Akkoc, N, Bautista-Molano, W, Burgos-Vargas, R, Wei, JC, Chiowchanwisawakit, P, Dougados, M, Duruoz, MT, Elzorkany, BK, Gaydukova, I, Gensler, LS, Gilio, M, Grazio, S, et al., Van den Bosch, FE, et al. Measurement properties of the ASAS Health Index: results of a global study in patients with axial and peripheral spondyloarthritis Ann Rheum Dis 77, 1311-1317, 2018. (Epub 2018 Sep)
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Kip, E, Staal, J, Tima, HG, Verstrepen, L, Romano, M, Lemeire, K, Suin, V, Hamouda, A, Baens, M, Libert, C, Kalai, M, Van Gucht, S, Beyaert, R. Inhibition of MALT1 decreases neuroinflammation and pathogenicity of virulent rabies virus in mice J Virol 92, e00720-18, 2018. (Epub 2018 Aug 29)
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Kip, E, Staal, J, Verstrepen, L, Tima, HG, Terryn, S, Romano, M, Lemeire, K, Suin, V, Hamouda, A, Kalai, M, Beyaert, R, Van Gucht, S. MALT1 controls attenuated rabies virus by inducing early inflammation and T cell activation in the brain J Virol 92, e02029-17, 2018. (Epub 2018 Jan 26)
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Kiss, M, Van Gassen, S, Movahedi, K, Saeys, Y, Laoui, D. Myeloid cell heterogeneity in cancer: not a single cell alike Cell Immunol 330, 188-201, 2018. (Epub 2018 Feb 14)
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Kloppenburg, M, Ramonda, R, Bobacz, K, Kwok, WY, Elewaut, D, Huizinga, TWJ, Kroon, FPB, Punzi, L, Smolen, JS, Vander Cruyssen, B, Wolterbeek, R, Verbruggen, G, Wittoek, R. Etanercept in patients with inflammatory hand osteoarthritis (EHOA): a multicentre, randomised, double-blind, placebo-controlled trial Ann Rheum Dis 77, 1757-1764, 2018. (Epub 2018 Oct 3)
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Krols, M, Detry, S, Asselbergh, B, Almeida-Souza, L, Kremer, A, Lippens, S, De Rycke, R, De Winter, V, Muller, FJ, Kurth, I, McMahon, HT, Savvides, SN, Timmerman, V, Janssens, S. Sensory-Neuropathy-Causing Mutations in ATL3 Cause Aberrant ER Membrane Tethering Cell Rep 23, 2026-2038, 2018. (Epub 2018 May 15)
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Krysko, DV, Ravichandran, KS, Vandenabeele, P. Macrophages regulate the clearance of living cells by calreticulin Nat Commun 9, 4644, 2018. (Epub 2018 Nov 7)
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Laloo, F, Herregods, N, Jaremko, JL, Carron, P, Elewaut, D, Van den Bosch, F, Verstraete, K, Jans, L. New bone formation in the intervertebral joint space in spondyloarthritis: An MRI study Eur J Radiol 109, 210-217, 2018. (Epub 2018 Dec)
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Lambrecht, BN. FcRn is mother's milk to allergen tolerance J Exp Med 215, 1-3, 2018. (Epub 2017 Dec 1)
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Lambrecht, BN, Vanderkerken, M, Hammad, H. The emerging role of ADAM metalloproteinases in immunity Nat Rev Immunol 18, 745-758, 2018. (Epub 2018 Sep 21)
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Lan, F, Zhang, N, Holtappels, G, De Ruyck, N, Krysko, O, Van Crombruggen, K, Braun, H, Johnston, SL, Papadopoulos, NG, Zhang, L, Bachert, C. Staphylococcus aureus Induces a Mucosal Type 2 Immune Response via Epithelial Cell-derived Cytokines Am J Respir Crit Care Med 198, 452-463, 2018. (Epub 2018 Aug 15)
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Lazzarano, S, Kucka, M, Castro, JPL, Naumann, R, Medina, P, Fletcher, MNC, Wombacher, R, Gribnau, J, Hochepied, T, Van Montagu, M, Libert, C, Chan, YF. Genetic mapping of species differences via in vitro crosses in mouse embryonic stem cells Proc Natl Acad Sci U S A 115, 3680-3685, 2018. (Epub 2018 Mar 21)
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Lembo-Fazio, L, Billod, JM, Di Lorenzo, F, Paciello, I, Pallach, M, Vaz-Francisco, S, Holgado, A, Beyaert, R, Fresno, M, Shimoyama, A, Lanzetta, R, Fukase, K, Gully, D, Giraud, E, Martin-Santamaria, S, Bernardini, ML, Silipo, A. Bradyrhizobium Lipid A: Immunological Properties and Molecular Basis of Its Binding to the Myeloid Differentiation Protein-2/Toll-Like Receptor 4 Complex Front Immunol 9, e1888, 2018. (Epub 2018 Aug 14)
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Lienart, S, Merceron, R, Vanderaa, C, Lambert, F, Colau, D, Stockis, J, van der Woning, B, De Haard, H, Saunders, M, Coulie, PG, Savvides, SN, Lucas, S. Structural basis of latent TGF-beta1 presentation and activation by GARP on human regulatory T cells Science 362, 952-956, 2018. (Epub 2018 Nov 23)
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Linero, F, Sepulveda, C, Christopoulou, I, Hulpiau, P, Scolaro, L, Saelens, X. Neutralization of Junin virus by single domain antibodies targeted against the nucleoprotein Sci Rep 8, 11451, 2018. (Epub 2018 Jul 30)
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Liu, J, Xiong, R, Brans, T, Lippens, S, Parthoens, E, Zanacchi, FC, Magrassi, R, Singh, SK, Kurungot, S, Szunerits, S, Bove, H, Ameloot, M, Fraire, JC, Teirlinck, E, Samal, SK, De Rycke, R, Houthaeve, G, De Smedt, SC, Boukherroub, R, et al.. Repeated photoporation with graphene quantum dots enables homogeneous labeling of live cells with extrinsic markers for fluorescence microscopy Light Sci Appl 7, 47, 2018. (Epub 2018 Aug 8)
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Lork, M, Kreike, M, Staal, J, Beyaert, R. Importance of Validating Antibodies and Small Compound Inhibitors Using Genetic Knockout Studies-T Cell Receptor-Induced CYLD Phosphorylation by IKKepsilon/TBK1 as a Case Study Front Cell Dev Biol 6, 40, 2018. (Epub 2018 Apr 10)
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Lou, B, De Beuckelaer, A, Dakwar, GR, Remaut, K, Grooten, J, Braeckmans, K, De Geest, BG, Mastrobattista, E, De Koker, S, Hennink, WE. Post-PEGylated and crosslinked polymeric ssRNA nanocomplexes as adjuvants targeting lymph nodes with increased cytolytic T cell inducing properties J Control Release 284, 73-83, 2018. (Epub 2018 Jun 14)
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Mahler, A, Balogh, A, Csizmadia, I, Klug, L, Kleinewietfeld, M, Steiniger, J, Susnjar, U, Muller, DN, Boschmann, M, Paul, F. Metabolic, Mental and Immunological Effects of Normoxic and Hypoxic Training in Multiple Sclerosis Patients: A Pilot Study Front Immunol 9, 2819, 2018. (Epub 2018 Nov 29)
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