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Selected IRC publications
The IRC publications that match your query are listed below.
For copyright reasons, PDF-versions of our publications are available on the intranet only (login required 
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Slowicka, K, Petta, I, Blancke, G, Hoste, E, Dumas, E, Sze, M, Vikkula, H, Radaelli, E, Haigh, J, Jonckheere, S, Taminau, J, Vandamme, N, Wullaert, A, Tulchinsky, E, Nittner, D, Van Vlierberghe, P, De Hertogh, G, Baldin, P, Etlioglu, E, et al. Berx, G, Vereecke, L, van Loo,G. Zeb2 drives invasive and microbiota-dependent colon carcinoma Nature Cancer 1, 620-634, 2020. (Epub 2020 Jun 15) 
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Souffriau, J, Timmermans, S, Vanderhaeghen, T, Wallaeys, C, Van Looveren, K, Aelbrecht, L, Dewaele, S, Vandewalle, J, et al., Eggermont, M, De Rycke, R, De Bruyne, M, Ballegeer, M, Vandevyver, S, Hochepied, T, Beyaert, R, Libert, C. Zinc inhibits lethal inflammatory shock by preventing microbe-induced interferon signature in intestinal epithelium EMBO Mol Med , e11917, 2020. (Epub 2020 Sep 11)
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Sprooten, J, De Wijngaert, P, Vanmeerbeerk, I, Martin, S, Vangheluwe, P, Schlenner, S, Krysko, DV, Parys, JB, Bultynck, G, Vandenabeele, P, Garg, AD. Necroptosis in Immuno-Oncology and Cancer Immunotherapy Cells 9, 1823, 2020. (Epub 2020 Aug 01)
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Staal, J. Fytohormonen : verschillende bioactieve moleculen die metabolisme en ontsteking beïnvloeden in de mens Bloedvaten, Hart, Longen 25, 32 - 35, 2020. (Epub 2020)
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Stijlemans, B, Korf, H, De Baetselier, P, Brys, L, Van Ginderachter, JA, Magez, S, De Trez, C. Hepatocyte-derived IL-10 plays a crucial role in attenuating pathogenicity during the chronic phase of T. congolense infection PLoS Pathog 16, e1008170, 2020. (Epub 2020 Feb 3)
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Teufelberger, AR, Van Nevel, S, Hulpiau, P, Nordengrun, M, Savvides, SN, De Graeve, S, Akula, S, Holtappels, G, De Ruyck, N, Declercq, W, Vandenabeele, P, Hellman, L, Broker, BM, Krysko, DV, Bachert, C, Krysko, O. Mouse Strain-Dependent Difference Toward the Staphylococcus aureus Allergen Serine Protease-Like Protein D Reveals a Novel Regulator of IL-33 Front Immunol 11, 582044, 2020. (Epub 2020 Sep 25)
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Thyssen, JP, Jakasa, I, Riethmuller, C, Schon, MP, Braun, A, Haftek, M, Fallon, PG, Wroblewski, J, Jakubowski, H, Eckhart, L, Declercq, W, Koppes, S, Engebretsen, KA, Bonefeld, C, Irvine, AD, Keita-Alassane, S, Simon, M, Kawasaki, H, Kubo, A, et al.. Filaggrin Expression and Processing Deficiencies Impair Corneocyte Surface Texture and Stiffness in Mice J Invest Dermatol 140, 615-623, 2020. (Epub 2019 Aug 31)
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Tipanee, J, Di Matteo, M, Tulalamba, W, Samara-Kuko, E, Keirsse, J, Van Ginderachter, JA, Chuah, MK, VandenDriessche, T. Validation of miR-20a as a Tumor Suppressor Gene in Liver Carcinoma Using Hepatocyte-Specific Hyperactive piggyBac Transposons Mol Ther Nucleic Acids 19, 1309-1329, 2020. (Epub 2020 Mar 6)
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Todorov, H, Cannoodt, R, Saelens, W, Saeys, Y. TinGa: fast and flexible trajectory inference with Growing Neural Gas Bioinformatics 36, i66-i74, 2020. (Epub 2020 Jul 1)
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Tougaard, P, Martinsen, LO, Lutzhoft, DO, Jensen, HE, Flethoj, M, Vandenabeele, P, Pedersen, AE, Skov, S, Hansen, AK, Hansen, CHF. TL1A regulates adipose-resident innate lymphoid immune responses and enables diet-induced obesity in mice Int J Obes (Lond) 44, 1062-1074, 2020. (Epub 2020 Jan 30)
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Trocha, KM, Kip, P, Tao, M, MacArthur, MR, Trevino-Villarreal, H, Longchamp, A, Toussaint, W, Lambrecht, BN, de Vries, MR, Quax, PHA, Mitchell, JR, Ozaki, CK. Short-Term Preoperative Protein Restriction Attenuates Vein Graft Disease via Induction of Cystathionine Upsilon-Lyase Cardiovasc Res 116, 416–428, 2020. (Epub 2019 Mar 29)
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Van Coillie, S, Wiernicki, B, Xu, J. Molecular and Cellular Functions of CTLA-4 Adv Exp Med Biol 1248, 7-32, 2020. (Epub 2020 Mar 18)
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Vandaele, R, Saeys, Y, De Bie, T. Mining Topological Structure in Graphs through Forest Representations Journal of Machine Learning Research 21, 1-68, 2020. (Epub Oct 2020)
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Van Damme, KFA, Tavernier, S, Van Roy, N, De Leeuw, E, Declercq, J, Bosteels, C, Maes, B, De Bruyne, M, Bogaert, D, Bosteels, V, Hoste, L, Naesens, L, Maes, P, Grifoni, A, Weiskopf, D, Sette, A, Depuydt, P, Van Braeckel, E, Haerynck, F, et al.. Case Report: Convalescent Plasma, a Targeted Therapy for Patients with CVID and Severe COVID-19 Front Immunol 11, 596761, 2020. (Epub 2020 Nov 20)
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Vandamme, N, Denecker, G, Bruneel, K, Blancke, G, Akay, O, Taminau, J, De Coninck, J, De Smedt, E, Skrypek, N, Van Loocke, W, et al.,Nittner, D, Kohler, C, et al.,Bouchez, L, et al, Andries, V, Rambow, F, Van Vlierberghe, P, Goossens, S, van den Oord, J, Marine, J-C, Berx, G The EMT transcription factor ZEB2 promotes proliferation of primary and metastatic melanoma while suppressing an invasive, mesenchymal-like phenotype Cancer Res 80, 2983-2995, 2020. (Epub 2020 Jun 5)
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Van den Berge, K, Roux de Bezieux, H, Street, K, Saelens, W, Cannoodt, R, Saeys, Y, Dudoit, S, Clement, L. Trajectory-based differential expression analysis for single-cell sequencing data Nat Commun 11, 1201, 2020. (Epub 2020 Mar 5)
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Van den Broek, B, Pintelon, I, Hamad, I, Kessels, S, Haidar, M, Hellings, N, Hendriks, JJA, Kleinewietfeld, M, Brone, B, Timmerman, V, Timmermans, JP, Somers, V, Michiels, L, Irobi, J. Microglial derived extracellular vesicles activate autophagy and mediate multi-target signaling to maintain cellular homeostasis Journal of Extracellular Vesicles 10, e12022, 2020. (Epub 2020 Nov 25)
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Vandendriessche, C, Bruggeman, A, Van Cauwenberghe, C, Vandenbroucke, RE. Extracellular Vesicles in Alzheimer's and Parkinson's Disease: Small Entities with Large Consequences Cells 9, 2485, 2020. (Epub 2020 Nov 15)
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Vanderhaeghen, T, Vandewalle, J, Libert, C. Hypoxia-inducible factors in metabolic reprogramming during sepsis FEBS J 287, 1478-1495, 2020. (Epub 2020 Jan 23)
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Van der Jeught, K, Sun, Y, Fang, Y, Zhou, Z, Jiang, H, Yu, T, Yang, J, Kamocka, MM, So, KM, Li, Y, Eyvani, H, Sandusky, GE, Frieden, M, Braun, H, Beyaert, R, He, X, Zhang, X, Zhang, C, Paczesny, S, et al.. ST2 as checkpoint target for colorectal cancer immunotherapy JCI Insight 5, 136073, 2020. (Epub 2020 May 7)
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Vanderkerken, M, Maes, B, Vandersarren, L, Toussaint, W, Deswarte, K, Vanheerswynghels, M, Pouliot, P, Martens, L, Van Gassen, S, Arthur, CM, Kirkling, ME, Reizis, B, Conrad, D, Stowell, S, Hammad, H, Lambrecht, BN. TAO-kinase 3 governs the terminal differentiation of NOTCH2-dependent splenic conventional dendritic cells Proc Natl Acad Sci U S A 117, 31331-31342, 2020. (Epub 2020 Nov 19)
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Van de Sande, B, Flerin, C, Davie, K, De Waegeneer, M, Hulselmans, G, Aibar, S, Seurinck, R, Saelens, W, Cannoodt, R, Rouchon, Q, Verbeiren, T, De Maeyer, D, Reumers, J, Saeys, Y, Aerts, S. A scalable SCENIC workflow for single-cell gene regulatory network analysis Nat Protoc 15, 2247-2276, 2020. (Epub 2020 Jun 19)
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Vandewalle, J, Libert, C. GILZ in sepsis: "Poor is the pupil who does not surpass his master" Eur J Immunol 50, 490-493, 2020. (Epub 2020 Feb 27)
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Vandewalle, J, Libert, C. Glucocorticoids in Sepsis: To Be or Not to Be Front Immunol 11, 1318, 2020. (Epub 2020 Jul 21)
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Vandewalle, J, Vanderhaeghen, T, Beyaert, R, Libert, C. Taking the STING Out of Sepsis? Cell Host Microbe 27, 491-493, 2020. (Epub 2020 Apr 8)
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Van Dingenen, J, Pieters, L, Van Nuffel, E, Lefebvre, RA. Hemin reduces postoperative ileus in a heme oxygenase 1-dependent manner while dimethyl fumarate does without heme oxygenase 1-induction Neurogastroenterol Motil , e13624, 2020. (Epub 2019 May 23)
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Van Gassen, S, Gaudilliere, B, Angst, MS, Saeys, Y, Aghaeepour, N. CytoNorm: A Normalization Algorithm for Cytometry Data Cytometry A , in press, 2020. (Epub 2019 Oct 21)
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Van Gorp, H, Huang, L, Saavedra, P, Vuylsteke, M, Asaoka, T, Prencipe, G, Insalaco, A, Ogunjimi, B, Jeyaratnam, J, Cataldo, I, Jacques, P, Vermaelen, K, Dullaers, M, Joos, R, Sabato, V, Stella, A, Frenkel, J, De Benedetti, F, Dehoorne, J, et al.. Blood-based test for diagnosis and functional subtyping of familial Mediterranean fever Ann Rheum Dis 79, 960-968, 2020. (Epub 2020 Apr 20)
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Van Hove, H, Pombo Antunes, AR, De Vlaminck, K, Scheyltjens, I, Van Ginderachter, JA, Movahedi, K. Identifying the variables that drive tamoxifen-independent CreERT2 recombination: Implications for microglial fate mapping and gene deletions Eur J Immunol 50, 459-463, 2020. (Epub 2019 Nov 30)
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Van Looveren, K, Timmermans, S, Vanderhaeghen, T, Wallaeys, C, Ballegeer, M, Souffriau, J, Eggermont, M, Vandewalle, J, Van Wyngene, L, De Bosscher, K, Libert, C. Glucocorticoids limit lipopolysaccharide-induced lethal inflammation by a double control system EMBO Rep 21, e49762, 2020. (Epub 2020 May 8)
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Van Looveren, K, Van Wyngene, L, Libert, C. An extracellular microRNA can rescue lives in sepsis EMBO Rep , e49193, 2020. (Epub 2019 Nov 14)
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Van Looveren, K, Wallaeys, C, Libert, C. Potential of glucocorticoids to treat intestinal inflammation during sepsis Curr Opin Pharmacol 53, 1-7, 2020. (Epub 2020 Jan 25)
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Van Nuffel, E, Staal, J, Baudelet, G, Haegman, M, Driege, Y, Hochepied, T, Afonina, IS, Beyaert, R. MALT1 targeting suppresses CARD14-induced psoriatic dermatitis in mice EMBO Rep 21, e49237, 2020. (Epub 2020 Apr 28)
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van Olst, L, Verhaege, D, Franssen, M, Kamermans, A, Roucourt, B, Carmans, S, Ytebrouck, E, van der Pol, SMA, Wever, D, Popovic, M, Vandenbroucke, RE, Sobrino, T, Schouten, M, de Vries, HE. Microglial activation arises after aggregation of phosphorylated-tau in a neuron-specific P301S tauopathy mouse model Neurobiol Aging 89, 89-98, 2020. (Epub 2020 Jan 10)
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Vanslembrouck, B, Kremer, A, Van Roy, F, Lippens, S, van Hengel, J. Unravelling the ultrastructural details of alphaT-catenin-deficient cell-cell contacts between heart muscle cells by the use of FIB-SEM J Microsc 279, 189–196 , 2020. (Epub 2019 Dec 11)
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Van Wyngene, L, Vanderhaeghen, T, Timmermans, S, Vandewalle, J, Van Looveren, K, Souffriau, J, Wallaeys, C, Eggermont, M, Ernst, S, Van Hamme, E, Goncalves, A, Eelen, G, Remmerie, A, Scott, CL, Rombouts, C, Vanhaecke, L, De Bus, L, Decruyenaere, J, Carmeliet, P, et al.. Hepatic PPARalpha function and lipid metabolic pathways are dysregulated in polymicrobial sepsis EMBO Mol Med , e11319, 2020. (Epub 2020 Jan 9)
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Verboom, L, Martens, A, Priem, D, Hoste, E, Sze, M, Vikkula, HK, Van Hove, L, Voet, S, Roels, J, Maelfait, J, Bongiovanni, L, de Bruin, A, Scott, CL, Saeys, Y, Pasparakis, M, Bertrand, MJM, van Loo, G. OTULIN Prevents Liver Inflammation and Hepatocellular Carcinoma by Inhibiting FADD- and RIPK1 Kinase-Mediated Hepatocyte Apoptosis Cell Rep 30, 2237-2247, 2020. (Epub 2020 Feb 18)
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Vlaminck, S, Acke, F, Prokopakis, E, Speleman, K, Kawauchi, H, van Cutsem, JC, Hellings, PW, Jorissen, M, Seys, S, Bachert, C, Zele, TV, Lambrecht, BN, Gevaert, P. Surgery in Nasal Polyp Patients: Outcome After a Minimum Observation of 10 Years Am J Rhinol Allergy in press, , 2020. (Epub 2020 Oct 5)
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Vroman, H, van Uden, D, Bergen, IM, van Hulst, JAC, Lukkes, M, van Loo, G, Clausen, BE, Boon, L, Lambrecht, BN, Hammad, H, Hendriks, RW, Kool, M. Tnfaip3 expression in pulmonary conventional type 1 Langerin-expressing dendritic cells regulates T helper 2-mediated airway inflammation in mice Allergy 75, 2587-2598, 2020. (Epub 2020 Apr 23)
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Wang, B, Van Herck, S, Chen, Y, Bai, X, Zhong, Z, Deswarte, K, Lambrecht, BN, Sanders, NN, Lienenklaus, S, Scheeren, HW, David, SA, Kiessling, F, Lammers, T, De Geest, BG, Shi, Y. Potent and Prolonged Innate Immune Activation by Enzyme-Responsive Imidazoquinoline TLR7/8 Agonist Prodrug Vesicles J Am Chem Soc 142, 12133-12139, 2020. (Epub 2020 Jun 11)
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Wendrich, JR, Yang, B, Vandamme, N, Verstaen, K, Smet, W, Van de Velde, C, Minne, M, Wybouw, B, Mor, E, Arents, HE, Nolf, J, Van Duyse, J, Van Isterdael, G, Maere, S, Saeys, Y, De Rybel, B. Vascular transcription factors guide plant epidermal responses to limiting phosphate conditions Science 370, eaay4970eaay4970, 2020. (Epub 2020 Sep 17)
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Wiernicki, B, Dubois, H, Tyurina, YY, Hassannia, B, Bayir, H, Kagan, VE, Vandenabeele, P, Wullaert, A, Vanden Berghe, T. Excessive phospholipid peroxidation distinguishes ferroptosis from other cell death modes including pyroptosis Cell Death Dis 11, 922, 2020. (Epub 2020 Oct 27)
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Yang, J, Antin, P, Berx, G, Blanpain, C, Brabletz, T, Bronner, M, Campbell, K, Cano, A, Casanova, J, Christofori, G, Dedhar, S, Derynck, R, Ford, HL, Fuxe, J, Garcia de Herreros, A, Goodall, GJ, Hadjantonakis, AK, Huang, RJY, Kalcheim, C, et al.. Guidelines and definitions for research on epithelial-mesenchymal transition Nat Rev Mol Cell Biol 21, 341-352, 2020. (Epub 2020 Apr 16)
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Yao, M, Ventura, PB, Jiang, Y, Rodriguez, FJ, Wang, L, Perry, JSA, Yang, Y, Wahl, K, Crittenden, RB, Bennett, ML, Qi, L, Gong, CC, Li, XN, Barres, BA, Bender, TP, Ravichandran, KS, Janes, KA, Eberhart, CG, Zong, H. Astrocytic trans-Differentiation Completes a Multicellular Paracrine Feedback Loop Required for Medulloblastoma Tumor Growth Cell 180, 502-520, 2020. (Epub 2020 Jan 23)
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Ydens, E, Amann, L, Asselbergh, B, Scott, CL, Martens, L, Sichien, D, Mossad, O, Blank, T, De Prijck, S, Low, D, Masuda, T, Saeys, Y, Timmerman, V, Stumm, R, Ginhoux, F, Prinz, M, Janssens, S, Guilliams, M. Profiling peripheral nerve macrophages reveals two macrophage subsets with distinct localization, transcriptome and response to injury Nat Neurosci 23, 676-689, 2020. (Epub 2020 Apr 13)
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Amaral, AC, Saavedra, PHV, Oliveira Souza, AC, de Melo, MT, Tedesco, AC, Morais, PC, Soares Felipe, MS, Bocca, AL. Miconazole loaded chitosan-based nanoparticles for local treatment of vulvovaginal candidiasis fungal infections Colloids Surf B Biointerfaces 174, 409-415, 2019. (Epub 2019 Feb 1)
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Andries, V, De Keuckelaere, E, Staes, K, Hochepied, T, Taminau, J, Lemeire, K, Birembaut, P, Berx, G, van Roy, F. A new mouse model to study the role of ectopic Nanos3 expression in cancer BMC Cancer 19, 598, 2019. (Epub 2019 Jun 17)
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Antonioli, L, Blandizzi, C, Pacher, P, Guilliams, M, Hasko, G. Rethinking Communication in the Immune System: The Quorum Sensing Concept Trends Immunol 40, 88-97, 2019. (Epub 2019 Jan 2)
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Arandjelovic, S, Perry, JSA, Lucas, CD, Penberthy, KK, Kim, TH, Zhou, M, Rosen, DA, Chuang, TY, Bettina, AM, Shankman, LS, Cohen, AH, Gaultier, A, Conrads, TP, Kim, M, Elliott, MR, Ravichandran, KS. A noncanonical role for the engulfment gene ELMO1 in neutrophils that promotes inflammatory arthritis Nat Immunol 20, 141-151, 2019. (Epub 2019 Jan 14)
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Ballegeer, M, Vandewalle, J, Eggermont, M, Van Isterdael, G, Dejager, L, De Bus, L, Decruyenaere, J, Vandenbroucke, RE, Libert, C. Overexpression of Gilz Protects Mice Against Lethal Septic Peritonitis Shock 52, 208-214, 2019. (Epub 2018 Aug 17)
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